Former Fellows

Fellow 1994-2000

Research Interests
Microtubule protein motors: their regulation, diversity and function; their role in membrane trafficking.

Other Information
Granted a one-year extension to 30.9.00
Appointed Lecturer 1.10.00
Elected a Member of the Institute, 2001
Promoted to Senior Lecturer from 1.10.02
Promoted to Professor of Cell Biology, August 2007

Fellow 1984-1985

Research Interests
Has worked in the vaccines industry since 1998. General interest in the pathogenesis and immunobiology of infectious diseases and in human vaccine research and development. Broader interest and expertise in the Biotechnology and Pharmaceuticals industry.

Other Information
Presenter of the 6th Sir Henry Dale Lecture, 1984
Winner of the SGM Fleming Award 1985
Resigned fellowship on appointment as Professor of Microbiology, University of Reading, 1985
Winner, Univ Section, Toshiba Year of Invention, 1988
Visiting Research Fellow, CIBA-GEIGY, 1989-1990
Head, School of Animal & Microbial Sciences, 1990-1994
Elected a Member of the Institute, 1993
Member of SEAC (Spongiform Encephalopathy Advisory Committee) 1995-2000
Appointed Vice President of R&D (France) Pasteur Mérieux Connaught, 1999
Appointed Vice President Discovery & External R & D, Aventis Pasteur, 2001
Senior Vice President for Research & External R & D, Aventis Pasteur, 2003
Elected Fellow of Academy of Medical Sciences, 2007
Appointed to MRC Council 2008-12
Retired from Sanofi Pasteur, October 2013
Retired from MRC Council, 2014 (after 6 years in post)
Visiting Professor of Microbiology at University of Reading 1998-present
Visiting Professor at the Sir William Dunn School of Pathology, University of Oxford, 2013-present

Fellow 2016- 2021

Research Interests
Regulation of stem cell potential in mammalian endocrine organs (pituitary gland and adrenal medulla)

Other Information:
Elected to membership of the Institute, 2021
Promoted to Professor, 2024
Executive Committee member for the European Society for Endocrinology 2022-2026
Congress Chair for the European Congress of Endocrinology 2022-2026
Starling Medal 2022 (Society for Endocrinology)

Fellow 2002-2007

Research Interests
Gene expression and cell signalling dynamics in Drosophila.

Other Information
EMBO Young Investigator Award, 2003
Elected a member of the Institute, 2008
Promoted to Professor of Cell and Developmental Biology, 2013
Elected a Fellow of the Royal Society of Biology, 2014

Fellow 2014-2019

Research Interests
Dynamics of tRNA abundance and the regulation of protein expression levels

Other Information
Elected as a member of EMBO
Awarded Francis Crick Medal from the Royal Society
Elected a Member of the Institute, 2018
Endowed Chair in Biomedical Data Science
Director, Center for Data Driven Discovery
Member, Department of Structural Biology
Elected member of the Institute, 2019
Awarded EMBO Gold medal, 2019

Research Interests

Anisotropic retinal circuits for processing of colour and space in nature.

Other Information

MIT Technology Review, Europe. ​ “Innovators under 35″, 2016
ERC-Starter Grant 2016
Eppendorf & Nature. Young European Investigator Award, 2017
Elected Fellow, Royal Society of Biology (FRSB), 2019
Granted Wellcome Trust Investigator Award, 2020
Awarded Nature Research Award for Driving Global Impact, 2019
Awarded the Boehringer Igeleim FENS research Awards, 2022
Voted onto the IBRO PERC Committee, 2022
Elected Member of EMBO, 2023
Wellcome Investigator Award 2021
ERC-Advanced Grant 2024
Director of Sussex Neuroscience 2025 –

Fellow 1990-1997

Research Interests
Molecular mechanisms underlying the long term persistence of bacterial infections in bones and joints.

Other Information
Elected to a three-year non-stipendiary medical research fellowship at Corpus Christi College, Oxford, June 1992
Appointed Hon Senior Registrar with Oxford RHA for one year from 1.10.92 and granted unpaid leave of absence during this period
Granted further year’s unpaid leave of absence to 31.12.94
Promoted to Hon Consultant status from 1.1.95
Resigned fellowship to take up appointment as Consultant Physician in Charge of the Bone Infection Unit at the Nuffield Orthopaedic Centre, Oxford, from 1.9.97
Elected a Member of the Institute, 1998
Medical Director, Nuffield Orthopaedic Centre, 2003

Fellow 1999-2005

Research Interests
Mycobacterial cell wall biosynthesis: structure, function and biological implications in tuberculosis.

Other Information
Lister Institute-Jenner Fellow
Awarded the 1999 W.H. Pierce Prize from the Society of Applied Microbiology
Promoted to Professor of Microbial Physiology, 2000
Granted unpaid leave from 1.2.02 to 1.8.02 to re-establish research (fellowship now finishes 31.3.05)
Elected a Member of the Institute, 2006
The Biochemical Society: Biochemical Society Award, 2008

Fellow 1991-1996

Research Interests
Chromatin and nuclear organisation of the mammalian genome, gene packaging and organisation within the chromosomes.

Other Information
Appointed Senior Scientist in the MRC Human Genetics Unit, 1.10.96
1997 Genetical Society Balfour Lecturer
Elected a Member of the Institute, 1997
Awarded the James S. McDonnell Foundation Centennial Fellowship in Human Genetics, 1999
Elected a member of EMBO, 2001
Nominated as Charles Darwin Award Lecturer 2001, at the BAAS
Appointed Hon Lecturer, University of Edinburgh
Elected Fellow of the Royal Society of Edinburgh, 2005
Elected a Member of the Institute’s Scientific Advisory Committee, 2008
Appointed Head of Section: Chromosome and Gene Expression, MRC Human Genetics Unit, 2009
Elected Fellow of the Academy of Medical Science, 2005
Elected a Member of the Institute’s Scientific Advisory Committee, 2008-2013
Head of Chromosome & Gene Expression, MRC Human Genetics Unit, 2009
Appointed to Institute’s Governing Body, 2013, re-elected 2018
President of the Genetics Society, 2015
Director MRC Human Genetics Unit, Edinburgh, 2015
Elected to the Royal Society, 2017
Awarded CBE, 2021
Elected as a Foreign Member of the National Academy of Sciences (USA)

Fellow 2005-2009

Research Interests
Functional genomics of malaria parasite development and mosquito transmission.

Other Information
Moved to Wellcome Trust Sanger Institute, 2007
Elected a Member of the Institute, 2010
Moved to Umeå University, Sweden, 2018
Appointed Professor Umeå University, Sweden, 2018
Director Molecular Infection Medicine Sweden 2018
ERC Advanced Grant, 2018

Fellow 1991-1996

Research Interests
Interests are chromosome replication and the cell cycle.

Other Information
Lister Institute-Jenner Fellow
Appointed Senior Scientist at ICRF from 1.7.96
Elected a Member of the Institute, 1997
Director, CRC Chromosome Replication Research Group, University of Dundee, from November 1997
Senior Lecturer in the Department of Biochemistry, University of Dundee, from 1.11.97
Elected member of EMBO, 1999
Appointed Reader 1.10.00
Awarded a personal chair in Chromosome Maintenance, November 2001
Elected a Fellow of the Royal Society of Edinburgh, March 2002
Elected Fellow of Academy of Medical Sciences, 2012
Appointed Dean of Research for College of Life Sciences, University of Dundee, August 2014
Appointed Dean of School of Life Sciences, University of Dundee, April 2016
Appointed member of the Institute’s Scientific Committee, 2019
Professor of Chromosome Maintenance and Pro-Vice Chancellor for Research & Innovation at the University of East Anglia, 2024

Research Interests
BREX and phage-bacteria interactions.

Fellow 1983-1987

Research Interests
Active in research management, education and administration. General interest in infectious diseases and viral infection processes.

Other Information
Temporary Clinical Senior Registrar 1.4.86 – 31.12.86
Hon Senior Lecturer/Consultant from 1.4.87
Appointed Wellcome Senior Lecturer, Addenbrooke’s Hospital, having resigned Lister Fellowship, 1.1.88
Appointed Lecturer in Medicine, University of Cambridge, 1988
Appointed Professor of Medicine, University of Wales College of Medicine, Cardiff, 1.1.91
Elected a Member of the Institute, 1993
Appointed to the Council of the MRC, 1995
Elected member of the Institute’s SAC, 1996
Appointed Chairman of the Molecular & Cell Medicines Board, 1996
Elected as Foreign Member of the Faculty of Natural Sciences of the Polish Academy of Arts & Science, 1998
Chairman of the Hospital-based Clinical Subjects Unit of Assessment Panel for the 2001 RAE
Founder Fellow of the Academy of Medical Sciences, 1998
Knighthood, New Year’s Honours List, 2001
Appointed Principal, Imperial College School of Medicine from 1.2.01
Appointed Chairman of the Joint Medical Advisory Committee to the Higher Education Funding Council 2002
Appointed Deputy Rector, Imperial College London, 1.10.04
Appointed Chief Executive, MRC, 2008
Elected a Fellow of the Royal Society, 2008
Appointed Vice Chancellor, University of Cambridge, 2010
Appointed Chairman, Cancer Research UK, 2017
Appointed Board Trustee, Nanyang Technological University Singapore, 2017
Appointed Governor, Director & Charity Trustee, Courtauld Institute of Art, 2019
Appointed Council Member, Imperial College London, August 2021
Chairman Diamond Light Source
GBE

Fellow 1999-2003

Research Interests
The regulation of gene activity: specifically, how the level of gene transcription is regulated after activation and how chromatin packaging is disrupted to allow accessibility to genetic information.

Other Information
Elected a Member of the Institute, 2004
Moved to the Department of Biochemistry & Molecular Biology, University of Leeds, 1.10.04 as a University Research Fellow

Fellow 2004-2015

Research Interests
Using yeast as a model system to understand the insulin-dependent trafficking of GLUT4 in adipocytes

Other Information
Prize Fellowship extended until 31.12.13
Promoted to Reader, August 2010
Fellowship extended to 31.08.15
Moved to University of York, 2014

Fellow 2008-2013

Research Interests
Molecular cell biology of cytoskeletal transport.

Other Information
Elected a member of the Institute 2014
Elected a member of EMBO, 2015

Fellow 2009-2014

Research Interests
Studying the emergence of neuronal circuits during brain development

Other Information
Elected a member of the Institute, 2015

Fellow 1985-1991

Research Interests
Generation of human antibodies in response to infectious agents, particularly HIV and the impact of this on vaccine design.

Other Information
Lister Institute-Jenner Fellow
Promoted to Senior Lecturer from 1.10.87
One year’s sabbatical at the Scripps Research Institute in La Jolla, July 1989 to August 1990
Fellowship extended by 2 yrs to Sept 1992 & sabbatical leave at the Scripps Inst extended by 1 yr to Aug 1991
Appointed Professor (Personal Chair) in the Department of Biochemistry from 1.10.90
Resigned fellowship on appointment to the staff of the Scripps Research Institute, La Jolla, on 1.10.91
1995-2005 NIH Merit Award
Elected a Member of the Institute 2003

Fellow 1994-1998

Research Interests
The cellular and developmental biology of the filamentous, antibiotic-producing bacteria Streptomyces. Fundamental aspects of bacterial transcription. The regulatory networks and cyclic nucleotide signalling events that control sporulation in Streptomyces.

Other Information
Appointed Group Leader, John Innes Centre, 1990
Elected a Member of the Institute, 1999
Appointed Professor, 2005
Elected a Fellow of the American Academy of Microbiology, 2009
Appointed Head, Department of Molecular Microbiology, John Innes Centre, 2012
Appointed to the Scientific Advisory Board of the Max Planck Institute for Terrestrial Microbiology, Marburg, Germany, 2017
Appointed to the Scientific Advisory Board of the Department of Microbiology of the Pasteur Institute, Paris, France, 2019
Appointed Co-Editor-in-Chief Current Opinion in Microbiology, 2022

Fellow 1997-2003

Research Interests
Immunological control of human persistent virus infections, particularly HCMV and HIV.

Other Information
Granted six months unpaid leave of absence for specialist training at Emory University, USA, from 1.4.01. Fellowship extended to 31.3.03
Elected a Member of the Institute, 2005

Fellow 1982-1984

Research Interests
Solution studies on the structure and dynamics of proteins, protein-protein complexes and protein nucleic acid complexes using a range of NMR spectroscopy methods.

Other Information
Resigned fellowship on appointment as Joint Head of the Biological NMR Group, Max-Planck Institute for Biochemistry, Munich, 1.10.84
Appointed Senior Investigator, Laboratory of Chemical Physics, National Institute of Diabetes & Digestive & Kidney Disease, NIH, Bethesda, Maryland, 1988
Scientific Achievement Award (Biological Sciences) Washington Academy of Sciences, 1989
Distinguished Young Scientist Award of the Maryland Academy of Sciences, 1990
Elected Fellow Royal Society of Chemistry (UK), 1990
Elected Fellow Washington Academy of Sciences, 1991
Appointed Chief, Protein NMR Section, Laboratory of Chemical Physics, 1991
Director’s Award, National Institutes of Health, 1992
National Institutes of Health Lecture, 1993
Dupont-Merck Young Investigator Award of the Protein Society, 1993
Appointed to Senior Biomedical Research Service, 1996
The Harrington Lecture, NIMR, 1996-1997
Elected Fellow of the American Association for the Advancement of Science (AAAS) 1999
Original member, Institute for Scientific Information (ISI) Highly Cited Researchers Database (2001)
Elected a Member of the Institute 2003
Elected Fellow of the Biophysical Society (USA), 2009
Hillebrand Award of the Washington Chapter of the American Chemical Society, 2010
Fellow American Academy of Arts and Sciences, 2010
Appointed NIH Distinguished Investigator, 2011
Elected a Fellow of the International Society of Magnetic Resonance for “Seminal contributions in the field of biological NMR”, 2011
Royal Society of Chemistry Centenary Prize, 2011
Biochemical Society 2013 Centenary Award and Sir Frederick Gowland Hopkins Memorial Lecture, 2012
Elected Member of the National Academy of Sciences (USA), 2014
Elected Foreign Member of Academia Europaea, 2015
Biophysical Society Innovation Award, 2020
Elected Fellow of the Royal Society, 2020
Biophysical Society Innovation Award, 2020
Khorana Prize of the Royal Society of Chemistry, 2021
Awarded honorary doctorate (DSc) from University College London, 2021
Biopolymers Murray Goodman Memorial Prize, 2021

Fellow 1986-1991

Research Interests
Role of lipids in cell signalling, physiology and exocytosis. Disease implications when lipid regulation breaks down.

Other Information
Promoted to Reader in Physiology & Biochemistry, 1992
Appointed Professor of Cell Physiology from 1.10.94
Elected a Member of the Institute, 1996

Fellow 1989-1994

Research Interests
Protein DNA interactions, DNA polymerases, DNA repair, restriction and modification.

Other Information
Promoted to Senior Lecturer from 1.1.91
Appointed Lister Institute Professor of Biochemistry at the University of Newcastle-upon-Tyne from 1.1.92, the Chair to continue in the Institute’s name until 30.9.94
Elected a Member of the Institute, 1996
MRC Senior Research Leave Fellow, 1.10.97-31.3.00

Research Interests

Analysis of the role of (p)ppGpp in staphylococcal infection using zebrafish as a model organism

Other Information

Awarded a Wellcome Trust Discovery Award, 2024

Fellow 2007-2012

Research Interests
The role of ATM and ATR in preventing genomic instability.

Other Information
Nominated EMBO Young Investigator member
Awarded European Research Council (ERC) start up
Moved to IFOM, Milan 2013
Elected a member of the Institute, 2014

Fellow 2002-2007

Research Interests
Maintenance of epigenetic state, with focus on Spatial organisation of DNA replication, with focus on expression and function of CIZ1 protein variants. Biomarker development based on CIZ1 variant expression in lung cancers.

Other Information
Transferred location of laboratory from Wellcome/CRC Institute, Cambridge, 01.02.02
Elected a Member of the Institute, 2008
Royal Society Leverhulme Senior Research Fellow 2019-2020
Founded Cizzle Biotech in 2006, listed 2021 to progress a blood test for the early detection of lung cancer

Fellow 1999-2003

Research Interests
We study the molecular mechanisms of protein sorting in mammalian cells and the fundamental role it plays in cell, tissue and organism-level function. Specifically, our mechanistic dissection of protein sorting within the endosomal network has provided the framework to understand and interpret the de-regulation of endosomal protein sorting observed in a broad array of human diseases. These include cardiovascular disease and neurological disorders, most notably Alzheimer disease and Parkinson disease, as well as metabolic disorders such a type 2 diabetes.

Other Information
Promoted to Professor, 2002
Elected a Member of the Institute, 2005
Royal Society Merit Award Holder, 2008
Biochemical Society Morton Lecture, 2010
Keith Stanley Lecture, 2011
Elected Fellow of the Academy of Medical Sciences, 2020
Royal Society Noreen Murray Research Professorship, 2021
Elected Member of EMBO, 2021

Fellow 2005-2010

Research Interests
Nanotubes and synapses in immune cell communication.

Other Information
Promoted to Professor of Molecular Immunology, 2008
Awarded Wolfson Royal Society Research Merit, 2008
Elected a Member of the Institute, 2011
Moved from Manchester University to become the Head of Life Sciences at Imperial College London, 2022
Author of four popular science books (all published by Penguin Random House): The Compatibility Gene (2013), The Beautiful Cure (2018), The Secret Body (2021), Self Defence (2025).
Awarded an MBE for services to science communication, 2025.

Fellow 2000-2002

Research Interests
Post-transcriptional regulation during neural stem cell development and synaptic plasticity in Drosophila: its function in health and disease.

Other Information
Resigned fellowship on the award of a Wellcome Trust Senior Research Fellowship 1.7.02
Elected a Member of the Institute 2003
Promoted to Chair of Cell Biology, University of Edinburgh, 2003
Moved to Oxford, 2007
Elected as EMBO member in 2010

Fellow 1996-2000

Research Interests
Molecular genetic epidemiology and mutation detection. Linking variations in specific genome regions to cardiovascular and metabolic risk traits and early growth.
Methodology for handling and analyzing large population DNA banks.

Other Information
Appointed to a Personal Chair in Human Genetics at the University of Southampton, 1.10.97
Appointed Head of Division, October 1999
Elected a Member of the Institute, 2002

Fellow 1996-2001

Research Interests
Structure and function of bacterial cell surface proteins. Engineering of virus-like particles for use as scaffolds for antigen assemblies in vaccine design. Immunological responses to vaccines and biotherapeutic drugs.

Other Information
Promoted to Senior Lecturer from 1.8.2000
Elected a Member of the Institute, 2002
Promoted to Reader, 2004

Fellow 1995-2001

Research Interests
Molecular regulation of apoptosis: its relationship to disease, particularly cancer. Drug induced apoptosis and its suppression. Validation and imple-mentation of pharmaco-kinetic and dynamic assays.

Other Information
Granted maternity leave from 17.2.97 to 18.5.97. Fellowship extended to 28.2.01
1998 Charles Darwin lecturer for the British Association for the Advancement of Science
Promoted to Reader, 1.10.98
Awarded personal chair in Molecular Pharmacology from 1.1.02 (to be held jointly with the Schools of Pharmacy & Pharmaceutical Sciences and of Biological Sciences)
Elected a Member of the Institute 2002
Appointed head of division of Physiology, Pharmacology & Toxicology, April 2003
Moved to Paterson Institute of Cancer Research as Senior Group Leader, Cell & Molecular Pharmacology, 1.9.03
Remains Professor of Pharmacy & Pharmacology, University of Manchester
Elected a Fellow of the Academy of Medical Sciences, 2016

Fellow 2002-2007

Research Interests
Interfaces between DNA double strand break repair and chromatin.

Other Information
Lister Institute-Jenner Fellow
Transferred location from Department of Biochemistry, University of Cambridge to Reader at University of Sussex, 2007
Elected a Member of the Institute, 2008
Professor, 2015
Transferred to Institute of Cancer Research, 2016

Fellow 1991-1996

Research Interests
Bacterial population genetics and the evolution of antibiotic resistance and virulence.

Other Information
Promoted to Grade III of the Research and Analogous Faculty Salary Scale, 1.9.93
Reader in Microbiology, School of Biological Sciences, University of Warwick from 1.3.96
Elected a Member of the Institute, 1997
Awarded a personal chair from 1.10.00

Fellow 2013 – 2019

Research Interests
Vaccine-induced immunity, with particular focus on antibody immunology and human malaria infection.

Other Information
Supernumerary Fellow of Merton College, October 2009
Jenner Investigator, December 2010
Associate Professor, University of Oxford, July 2014
Wellcome Trust Senior Fellow, August 2015
Appointed Professor of Vaccinology and Translational Medicine, August 2018
Extended Fellowship to September 2019
Elected a Member of the Institute, 2018
Elected Fellow of the Academy of Medical Sciences, 2025

Fellow 2011-2016

Research Interests
Prevention of deaths from pesticide self-poisoning
Clinical pharmacology of antidotes

Other Information
Awarded a personal chair October 2013
Elected to membership of the Institute, 2016
Awarded Cullen Gold Medal for the ‘Greatest Benefit to the Practice of Medicine’ Royal College of Physicians of Edinburgh , 2017
Director, Centre for Pesticide Suicide Prevention
Consultant Clinical Toxicologist, National Poisons Information Service – Edinburgh & Royal Infirmary of Edinburgh, NHS Lothian
Honorary Consul for Sri Lanka in Scotland
University of Edinburgh’s Chancellor’s Award, 2020

Fellow 1987-1995

Research Interests
Molecular approaches to the control of insect-born diseases with a particular interest in insect molecular biology, insect parasite interactions, transgenic tech-nology, gene structure and expression.

Other Information
1990 Genetical Society Balfour Lecturer
Fellowship extended by 3 years to 30.9.95
Promoted to Senior Lecturer from 1.10.93
Elected a Member of the Institute, 1996
Appointed Professor of Molecular Entomology, Keele University, 1999
Appointed as Faculty Research Director for Natural Sciences, 2014
Awarded Honorary Fellowship of the Royal Entomological Society, 2015
Honorary Fellow of the Royal Entomological Society (Hon. FRES),2017

Fellow 1996-2000

Research Interests
The pathogenesis of Pseudomonas aeruginosa infection, in particular the type III secretion system and associated toxins. Second interest is the pathgenesis of septic shock and the role of nitric oxide and of ENA/VASP proteins and their phosphorylation by nitric oxide.

Other Information
Lister Institute-Jenner Fellow
Fellowship deferred until 1.1.96 in order to complete clinical training
Promoted to Senior Lecturer and Hon Consultant, April 1996
Appointed Reader in Infectious Diseases 1.10.99
Elected a Member of the Institute 2002
Appointed Professor Molecular Microbiology, University of Glasgow from 1.11.03

Fellow 2008-2013

Research Interests
Translational research programme for prevention of oesophageal adenocarcinoma

Other Information
Fellow of the Academy of Medical Sciences, 2013
Elected a member of the Institute 2014
Member of the Governing Body for 6 years, 2015

Fellow 1989-1994

Research Interests
Sequence specific recognition of DNA by small molecules (drugs and other ligands), oligonucleotides and proteins. Novel DNA structures (triple helix and quadruplex formation).

Other Information
Promoted to Senior Lecturer from 1.10.92
Appointed Reader Division of Biochemistry & Molecular Biology, School of Biological Sciences from 1.10.94
Elected a Member of the Institute, 1996
Promoted to a personal chair in Biochemistry 1.7.00
Executive Editor, Nucleic Acids Research from 1.2.02
Appointed Head of Division of Biochemistry & Molecular Biology, 1.9.02
Taken a 50% position in July 2015 as Associate Director of the Faraday Institute for Science and Religion at St Edmund’s College, Cambridge, whilst retaining post in Southampton (reduced to 50%)
Retired 2022, Awarded Emeritus Professor of Biochemistry at Southampton University.
After retirement Keithwas ordained deacon in the Church of England in June 2024, and priest in 2025. Keith is serving as a non-stipendiary curate at Highfield Church in Southampton. He retains an active interest in Science-Faith discussions.

Fellow 1989-1995

Research Interests
Synthesis and evaluation of novel biologically active chemicals with relevance to drug development and delivery. (Inositol phosphate and carbohydrate phosphate analogues, enzyme substrates and inhibitors.)

Other Information
Lilly Prize for Pharmaceutical Excellence, 1993
Leave of absence granted to work at the Cancer Research Institute, Arizona State University for 6 months in 1994
Transferred to the Dept of Pharmacy, Manchester, 1994
Fellowship extended by 6 months to 30.9.95
Elected a Member of the Institute, 1996
Senior Lecturer from 1.10.97
Promoted to Reader, July 2009

Fellow 2008-2013

Research Interests
Endothelial guidance in vascular patterning

Other Information
Tenured Senior Group Leader, LRI, 2009
Awarded Walther Fleming Medal of the German Society for Cell Biology, 2009
Elected a member of the Institute 2014
Moved to Max Delbruck Center for Molecular Medicine, Berlin, 2014
Professor for Experimental Cardiovascular Research, Charité, Berlin
DZHK Professor (German Center for Cardiovascular Research) and BIH Professor (Berlin Institute of Health)
Spokesperson MDC Integrative Biomedicine and Head of Integrative Vascular Biology, Max-Delbrück Center for Molecular Medicine, Berlin

Fellow 2001-2006

Research Interests
Modulation of fetal cardiovascular function by reversible adverse intrauterine conditions: consequences for later life.

Other Information
Granted permission to spend the 9 months from 1.1.02 to 30.9.02 in Bolivia and Chile
Awarded Hon Professorship University of Chile, 2002
Promoted to Reader in Developmental Cardiovascular Physiology & Medicine
Elected a Member of the Institute, 2007
Royal Society Wolfson Research Merit Award
Netherlands Wim Schellekens Prize lecture
Inaugural Lang-Pardi Italy Foundation Award
Awarded personal chair, 2011
Section Editor, Pediatric Research, 2011
President’s Presenter Award. The Society for Reproductive Investigation 58th Annual Meeting, San Diego, USA, 2011
President’s Presenter Award. The Society for Reproductive Investigation 59th Annual Meeting,
San Diego, USA, 2012
The Giorgio Pardi Foundation President’s Presenter’s Awards. The Society for Reproductive Investigation 59th Annual Meeting, San Diego, USA, 2012
Gonville & Caius 1958 Endowed Lectureship in Medicine, 2012
The Giorgio Pardi Foundation President’s Presenter’s Awards. The Society for Reproductive Investigation 60th Annual Meeting, San Diego, USA, 2013
Associate Editor, Journal of Gynecology, Reproduction and Perinatology, 2013
Elected President of the Fetal & Neonatal Physiological Society, 2014
Reviewing Editor, The Journal of Physiology, 2014
Section Editor, Journal of Developmental Origins of Health & Disease, 2014
Associate Editor, American Journal of Physiology (Regulatory, Integrative and Comparative Physiology), 2014
President’s Presenter Award. The Society for Reproductive Investigation 62nd Annual Meeting, San Francisco, USA, 2015
Thomas McDonald Award of The Society for Reproductive Investigation 62nd Annual Meeting, San Francisco, USA, 2015
David Barker Memorial Prize Lecture, Portland, Oregon, USA, 2015.
Sir Peter Tizard Prize Lecture, Neonatal Society, Winchester, UK, 2015
Honorary Professor, Fourth Military Medical University, Xi’an, China, 2015
ScD Degree from the University of Cambridge, 2016
Nick Hales Medal from the International Society of Developmental Origins of Health and Disease, 2017
FRCOG awarded from the Royal College of Obstetrics & Gynaecology in recognition of scientific work and its translational impact to improve the health and wellbeing of pregnant women and their unborn children, 2017
Elected to Latin American Academy of Sciences, 2018

Research Interests
How cells adapt to centrosome and microtubule alterations and how these in turn impact cell physiology and pathology to develop better ways to combat cancer

Other Information
Elected a Member of the Institute, 2024
Award a CRUK Programme Foundation Award in 2021

Fellow 1992-1998

Research Interests
Regulation of glucose transport in insulin-sensitive tissues in health and disease. Single molecule imaging of plasma membrane proteins. Cellular and Subcellular analysis of metabolic processes.

Other Information
Appointed Senior Lecturer retrospectively from l.7.92
Promoted to Reader in the Department of Biochemistry and Molecular Biology from l.10.95
Fellowship extended by one year to 30.9.98
Awarded a Personal Chair in Membrane Biology, 1997
Elected a Member of the Institute, 1999
Deputy Head of Biochemistry and Microbiology Division 1998-2004
Wellcome Research Leave Fellowship, 2004-2007
Professor Cell Biology, 2005 – 2019
Associate Dean, Postgraduate Research, 2013-2016
Professor, University of Strathclyde, 2019 – present
Fellow of the Learned Society of Wales, elected 2025

Fellow 2006-2011

Research Interests
Cellular endocrinology of the gut-brain-pancreatic axis, including the involvement of gut hormones in human health and disease and the physiology underlying GLP-1 based weight loss drugs

Other Information
Elected a member of the Institute, 2012
Professor of Endocrine Physiology (University of Cambridge), 2012
Elected as Fellow of the Academy of Medical Sciences, 2015
Wellcome Trust Senior Investigator, 2015

Research Interests
Molecular mechanisms of Wnt/beta-catenin signalling, ADP-ribosylation and telomere maintenance

Other Information
Wellcome Trust Investigator Award, 2019
Cancer Research UK Programme Foundation Award, 2019
Deputy Head of the Division of Structural Biology, September 2019
Reader in Structural Biology and Cell Signalling, the Institute of Cancer Research, October 2019.
Professor of Structural Biology and Cell Signalling, 2022
Deputy Head, Division of Structural Biology, 2019
Deputy Dean (Biomedical Sciences), 2024
Member of The Lister Institute of Preventive Medicine, 2023

Fellow 1983-1998

Research Interests
Understanding the molecular mechanisms of cell injury and death in human disease and in response to toxins.
The role of antioxidants in nutrition, health and disease.
Natural and synthetic antioxidants as therapeutic agents, especially for neurodegenerative disease.
Fundamental mechanisms of the ageing process

Other Information
Previous Posts:
Head of Biochemistry Department, King’s College (1988-1990)
Professor of Medical Biochemistry in the Division of Pharmacology, University of London, King’s College, 1998-2000
Deputy Director, Office of Life Science, NUS 2001-03
Head, Department of Biochemistry, NUS 2000-2007
Executive Director, NUS Graduate School of Integrative Sciences & Engineering, 2003-2008
Deputy President (Research & Technology), NUS, 2006-May 2015
Senior Advisor to the President
NUS, Jun 2015-May 2018

Awards:
Award from the Institute of Scientific Information (ISI) Top Cited Scientist in the United Kingdom in Biomedical Sciences, 1999.
Chosen as a founder member of the ISI database of the world’s most influential scientists in Biology and Biochemistry, 2000.
Clarivate Analytics Highly Cited Scientist (cross-field)
Awarded by Thomson Reuters as one of the world’s most highly-cited researchers in Neurobiology & Behaviour, Pharmacology & Toxicology, Biology and Biochemistry.
Awarded lifetime membership of the Oxygen Club of California, 2002.
Awarded the status of “most cited scientist” in Agricultural Sciences, ranked 16 out of 1663 worldwide in ISI database, 2003.
Awarded Research Excellence Award, School of Medicine, NUS, 2005.
Laboratory ranked number 1 worldwide by highest citation score in Free Radical Research, 2007.
Awarded “Lifetime Achievement Award” by the Society for Free Radical Biology & Medicine in the USA, 2008.
Awarded by FEBS Letters as top reviewer for 2009-2010.
Awarded the Public Administration Medal (Silver) by the President of Singapore for contributions to Singapore, 2010.
Awarded by Campus Safety Health and Environmental Management Association (CSHEMA) as a “Campus Leader Who Cares” in 2011
Awarded the Ken Bowman Research Award for outstanding achievements in the field of cardiovascular research from the Institute of Cardiovascular Sciences (Canada) in 2011
Awarded status of “Redox Pioneer” by the high impact journal Antioxidants & Redox Signaling in 2011
Two research papers were recognized as Citation Classics by the Institute of Scientific Information (ISI) and a commentary published in Current Contents
Awarded NUS University Award – Outstanding Researcher Award in 2012
Recognised as a Fellow of the Society for Free Radical Biology and Medicine for outstanding contributions made to the association as well as the field of free radical chemistry, redox biology and antioxidants, 2012
Elected as a Fellow of the American Association for the Advancement of Science (AAAS), 2012
Awarded the Science and Technology Medal by the President of Singapore “for distinguished sustained and exceptional contributions to Singapore’s Science and Engineering landscape”, 2013
Received the Lifetime Achievement Award of the Singapore Neuroscience Association, 2014
Received the Society of Nutrition and Food Science Advances in Nutrition Research Award, 2015
Jan 2021 – Present Chairman, BMRC Advisory Council (BMAC), Agency for Science Technology and Research (A*STAR)
Jul 2021 – Present Distinguished Professor, NUS
Jun 2018 – Present Senior Advisor (Academic Appointments and Research Excellence), Office of the Provost, NUS
2018, Awarded a DSc honoris causa by King’s College London.
2018, Identified by Clarivate Analytics as a Highly-cited Scientist, for cross-field research.
2023, University Outstanding Service Award, NUS

Fellow 2016-2021

Research
In vivo kinetics and functional response of human mononuclear phagocytes during acute tissue inflammation

Other Information
Foulkes Foundation Medal 2019
Elected to the Academy of Medical Sciences, 2020
Elected to membership of the Institute, 2021
Cheryl Tickle Medal, 2025

Fellow 1988-1993

Research Interests
Understanding molecular mechanisms by which intracellular signalling enzymes (the phosphoinositide 3-kinases; P13Ks) and their lipid products regulate cellular processes (movement, survival and proliferation).

Other Information
Transferred to the Institute of Animal Physiology and Genetics Research, Babraham, on 1.10.90
Appointed a BBSRC Senior Research Fellow, 1993
Elected a Member of the Institute, 1996
Elected as a Fellow of the Royal Society, 2013

Research Interests
Salmonella Persister formation at the single cell level

Fellow 1992-1997

Research Interests
The neural regulation of reproductive functioning, specifically looking at the role of different neuronal cell types in the regulation of fertility using molecular, cellular and whole animal studies.

Other Information
Lister Institute-Jenner Fellow
Awarded the Drapers Research Fellowship, 1991-1994
Fellow of Pembroke College, 1994-2003
Elected a Member of the Institute, 1998
Awarded Benoit Prize, Société de Neuroendrocrinologie Expérimentale, France, 1998
Awarded Ernst Knobil Prize, University of Pittsburgh, USA, 2000
Appointed Professor in the Department of Physiology, University of Otago, Dunedin, 2002
Elected as Fellow of the Royal Society of New Zealand, 2007
Awarded Liley Medal, Health Research Council of New Zealand, 2009
Awarded Triennial Medal, Physiological Society of New Zealand, 2011
Awarded Distinguished Research Medal, University of Otago, 2011.
Mortyn Jones Medal, British Society for Neuroendocrinology, 2015
Appointed Professor of Neuroendocrinology, University of Cambridge, 2019.
Awarded Mike McClure Pioneer Prize, Frontiers in Reproduction, Woods Hole, USA, 2023

Fellow 1990-1995

Research Interests
Understanding the processes involved in immune cell recognition of antigens and in immune response initiation. Role of the transmembrane protein CD45 in lymphocyte activation and regulation.

Other Information
Elected a Member of the Institute, 1996

Fellow 1991-1996

Research Interests
Understanding biomolecular recognition at the atomic level. Specifically the dynamics and thermodynamics of biomolecular interactions using a range of biophysical techniques and molecular modeling.

Other Information
Promoted to Senior Lecturer from 1.10.92
Transferred as Reader in Chemistry to the University of St Andrews from 1.10.94
Appointed Professor of Biophysical Chemistry, 1.10.96
Elected a Member of the Institute, 1997
Elected a Fellow of the Royal Society of Edinburgh, 1998
Received Zeneca Award from the Biochemical Society, 1998
Appointed Professor of Structural Biology (NMR), University of Leeds, 1.3.99
Newcastle University as Pro-Vice-Chancellor of Science, Agriculture & Engineering, January 2012

Fellow 1994-1999

Research Interests
Study of large molecular assemblies and biopolymers to understand the chemistry of weak intermolecular forces (non-covalent interactions) through the determination of thermodynamic properties, computer modeling and molecular design.

Other Information
Appointed Reader retrospectively from 1.10.94
Zeneca Research Award for Organic Chemistry, 1995
Appointed Lister Institute Professor of Chemistry, 1997
Appointed Head of Organic Chemistry, 1998
Awarded the Corday-Morgan Medal, 1999
Elected a Member of the Institute, 2000
Appointed EPSRC senior research fellow, 2005
Elected a Fellow of the Royal Society, 2008
Awarded RSC Tilden Prize, 2009
Moved to University of Cambridge, 2014
Honorary Member of the Royal Irish Academy, 2015

Fellow 2009-2014

Microcephaly, genome stability, inflammation and growth

Other Information
MRC Senior Clinical Fellowship 2007-2012
Balfour Lectureship, Genetics Society, 2012
Transferred to Medical Research Council Institute of Genetics October 2011
GSK Prize, Biochemical Society, 2012
Elected to EMBO membership 2013
Promoted to Professor 2013
Fellow of Royal Society Edinburgh, 2014
Fellow of the Academy of Medical Sciences, 2014
Elected a member of the Institute 2015
Elected a Fellow of the Royal Society, 2020

Fellow 1986-1991

Research Interests
Neural basis for active listening through the investigation of how neurons in the hearing centres of the brain adapt to the statistics of sound stimulation, which constantly change in real-life environments, integrate other sensory and motor-related signals, and adjust to the abnormal auditory inputs resulting from hearing impairment.

Other Information
E.P. Abraham Cephalosporin Junior Research Fellow in Medical Sciences at Lincoln College, 1986-1989
Visiting worker at the Eye Research Institute, Boston, Mass., June to October 1988
Appointed Lecturer in Neurology & Medicine, Lincoln College, Oxford, 1989
1990 Wellcome Prize in Physiology
Elected Wellcome Senior Research Fellow, 1.2.91
Fellowship renewed in 2000 to 2006
Appointed a University Research Lecturer, 1996
Elected a Member of the Institute, 1996
Appointed Reader in Auditory Physiology, 2000
Elected to Senior Research Fellowship in Medical Sciences, Merton College, 2002
Co-Director, Oxford Hearing and Balance Centre, 2003
Professor of Neurophysiology, University of Oxford, 2004
Member of the National Committee of the British Neuroscience Association, 2004-2007
Wellcome Principal Research Fellow, 2006
Elected to a Supernumerary Fellowship, Merton College, Oxford, 2007
Editorial Board, Journal of Neuroscience, 2009-2015
Member of the Royal National Institute for Deaf People Medical Advisory Panel, 2007-2011
Director, Wellcome Trust 4 year doctoral training programme in Neuroscience, University of Oxford, 2010-2025
Chief Research Advisor, Deafness Research (UK), 2011/13
Fellow of the Academy of Medical Sciences, 2011
Editorial Board, Journal of Physiology, 2011-2019
Appointed Member of the Royal Society/Wellcome Trust Sir Henry Dale Fellowship Committee, 2012
Action on Hearing Loss PhD review panel, 2014-2017
Member of the Editorial Board, eLife, 2015, (Senior Editor since 2016)
Wellcome Principal Research Fellowship renewed, 2016
Director of the Centre for Integrative Neuroscience, Department of Physiology, Anatomy and Genetics, 2016
Elected as a Fellow of the Physiological Society, 2017
Elected as a Fellow of the Royal Society, 2018
Elected to a Sir Henry Savile Fellowship, Merton College Oxford, 2023
Elected as a Fellow of the Asia-Pacific Artificial Intelligence Association (AAIA), 2025

Fellow 1995-2000

Research Interests
Cancer biology: molecular control of cell proliferation and death. Specific interests in telomeres and telomerase, and p53 induced cell senescence.

Other Information
Appointed Senior Lecturer in Cancer Biology, University of Wales College of Medicine, from 1.10.96
Appointed Co-ordinator BBSRC’s “Strategic Initiative into Ageing”, May 1998 (for 4 years)
Elected a Member of the Institute, 2001
Awarded a personal chair in the Department of Pathology from 1.2.02

Fellow 1993-1996

Research Interests
The physiology and biochemistry of the malaria parasite.

Other Information
Staines Medical Research Fellow, Exeter College, Oxford, 1.10.92 to 30.9.95
Sub-Rector at Exeter College, Oxford, 1994/95
Senior Research Fellow in Physiology at Exeter College, Oxford, from 1.10.95 to 31.12.97
Resigned fellowship on 31.5.96 on taking up the Chair of Biology at the Australian National University (ANU), Canberra, on 1.6.96. Head of the Department of Biochemistry and Molecular Biology, from 1.12.96 – 31.5.09
Fellowship continued until 31.12.96
Awarded the Roche Medal of the Australian Society for Biochemistry & Molecular Biology, 2002
Elected a Member of the Institute, 2003
Elected to an Overseas Fellowship at Churchill College, Cambridge, 2003
Awarded Australian Society for Parasitology’s Bancroft-Mackerras Medal, 2008
Director ANU Research School of Biology 2009-2014
Dean, ANU College of Medicine, Biology and Environment, 2014-2017
Elected a Fellow of the Australian Academy of Health and Medical Sciences, 2017
Dean, ANU College of Science, 2017-2024
Dean, ANU College of Science & Medicine, 2025-present
Appointed Member of the Order of Australia (AM), 2023

Fellow 2010-2016

Research Interests
Miro family proteins as regulators of synaptic bioenergetics and a locus for mitochondrial dysfunction in neurological disease

Other Information
Extended Fellowship to 31 December 2016
Elected to membership of the Institute, 2016

Fellow 2011-2019

Research Interests
Understanding how CpG islands and chromatin regulate gene expression and development in mammals.

Other Information

Elected EMBO Young Investigator 2010
Francis Crick lecture, 2015
Elected to membership of the Institute 2016
Named Chair and Professor of Genetics, Department of Biochemistry, University of Oxford, 2017
Extended Fellowship to 31.12.19
Elected member of the Institute, 2019
Elected EMBO Member 2021

Fellow 2012-2018

Research Interests
Bacterial interference with the ubiquitin system

Other Information
EMBO Young Investigator, 2011-2014
EMBO member since 2014
Extended Fellowship to 31.3.18
Elected a member of the Institute, 2017
Moved to Walter & Eliza Hall Institute of Medical Research, Victoria, Australia, 2018

Fellow 1995-2000

Research Interests
Mechanisms of oxygen sensing and impact of hypoxia. The role of ion channels, neurotransmitters and neuromodulators in the maturation of oxygen sensing and the effect of hypoxia upon cardiorespiratory disease.

Other Information
Promoted to Senior Lecturer, 1.10.96
Appointed Reader from 1.8.97
Elected a Member of the Institute, 2001
Deputy Editor in Chief, Journal of Physiology, 2005
Appointed Director of the Institute of Clinical Sciences, University of Birmingham, 2015
Appointed Chair of the Physiological Society’s Publications Committee, 2015
Connections Editor, Experimental Physiology 2015
Physiological Society Otto Hutter Prizewinner 2016
Fellow, Physiological Society 2018

Fellow 1987-1992

Research Interests
Mechanisms regulating cancer cell growth and proliferation (particularly the pRb/E2F pathway). Transcription factors and co-activator proteins in co-ordinating the cell cycle and other physiological processes.

Other Information
Lister Institute-Jenner Fellow
Awarded a tenured position at NIMR from 1.10.92
Elected a Member of the Institute, November 1993
Appointed to the Cathcart Chair of Biochemistry at the University of Glasgow from 1.10.95
Chief Scientific Officer of Prolifix, from 1996
Elected to European Molecular Biology Organization (EMBO), 2003
Elected a Fellow of the Royal Society of Edinburgh, 2004
Moved to John Radcliffe Hospital, Oxford
Elected a Fellow of the Academy of Medical Sciences, 2008
Moved to Old Road Campus Research Building, Oxford, 2011

Fellow 2004-2009

Research Interests
Research on how viruses interact with and manipulate the host immune system to enable their replication.

Discovered the HUSH (Human Silencing Hub) complex, an epigenetic repressor complex that assembles heterochromatin and silences newly integrated retroviruses and mobile endogenous retrotransposons including LINE1 elements.

Other Information
Elected a Fellow Academy of Medical Sciences, 2004
Professor of Immunology and Medicine, University of Cambridge, 2005
Elected a Member of the Institute, 2010
Elected member of EMBO 2019
Wellcome Trust Infection and Immunity Panel, 2008-2010
Chairperson: Wellcome Trust ERG Panel, 2010-2013
Wellcome Trust Principal Research Fellow, 2013–present
Professoral Fellow of Darwin College, Cambridge, 2013–present
Winner GSK Discovery Fast Track Challenge, 2015
MRC Clinical Training and Career Development Panel, 2016–present

Fellow 1990-1995

Research Interests
Mitrochondrial DNA and genetics, mitochondrial gene expression, bio-energetics and biochemistry. Mitochondrial diseases.

Other Information
Appointed Lecturer in the Department of Neurology, University of Newcastle from 1.3.95
Elected a Member of the Institute, 1996
Appointed Reader in Molecular Neuroscience, 1.8.98
Appointed Professor of Molecular Neuroscience, 2000
Appointed Director of the Institute for Cell and Molecular Bioscience, 2011
Appointed Deputy Director, Wellcome Centre for Mitochondrial Research 2017

Fellow 1993-2000

Area of Current Research Interests
Gene therapy for neurological disorders, specifically brain tumours, Parkinson’s Disease and multiple sclerosis. Also interested in neuro-immunology and viral immunology and viral vectors for gene therapy.

Other Information
Promoted to Senior Lecturer from 1.10.94.
Appointed Lister Institute Professor of Molecular Medicine and Gene Therapy from 1.7.95.
Reviewer of Clinical Trials in Gene Therapy and advisor for the Gene Therapy Advisory Committee, 1996.
Fellowship extended by 2 years to 30.9.00.
Member of the MRC’s Medical Advisory Board, 1999.
Appointed Member of the “Biological Sub-Committee” of the UK Medicines Control Agency, 1999.
Ad-hoc advisor to the NIH-RAC Committee on Human Gene Transfer Protocols, 1999, 2000.
Awarded the ‘Brain Bursary’ to give the Annual Brain Bursary Lecture, 2000.
Appointed Director and head of the ‘Gene Therapeutics Research Institute’ at the Cedars-Sinai Medical Center, Los Angeles, and Professor of Medicine at the University of California, Los Angeles from September, 2001.

Fellow 2012-2018

Research Interests
Elucidating mechanisms of myelinated axon formation, function and repair using zebrafish

Other Information
Extended Fellowship to 30.09.18
Elected to membership of the Institute, 2017

Fellow 2008-2013

Research Interests
Functional parallels between HIV-1 budding and the last step of cell division

Other Information
Promoted to Senior Lecturer, 2008
Elected EMBO Young Investigator member, 2008
Professor of Viral Cell Biology, 2013
Elected a member of the Institute 2014
GlaxoSmithKline Award, Biochemical Society, 2014
Vice Dean (Research and Impact), Faculty of Life Sciences & Medicine at King’s College, London, 2018

Fellow 1991-1997

Research Interests
DNA gyrase and other DNA topoisomerases: structure, function and mechanisms of action; role in DNA replication, recombination and the control of gene expression. Antibiotic action and discovery. Galleria mellonella as a model for the human infant gut microbiome.

Other Information
Lister Institute-Jenner Fellow
Reader in the Department of Biochemistry, 1.10.94
Awarded Personal Chair in Biochemistry from 1.10.97
Executive Editor, Nucleic Acids Research 1998-2007
Elected a Member of the Institute, 1998
Head of Biol Chemistry, John Innes Centre, 2000-2016
Hon. Professor of Biological Science, UEA, from 1.8.01
Member of Faculty of 1000 (f1000), 2008
Fellow of the Royal Society of Chemistry, 2008
Gordon Conference Evaluation Committee, 2010-2017
Member of the Antibiotic Action Advisory Board, 2012-2019
Inspiralis Ltd. – Director, Founder, Consultant and Chairman of the Board, 2005
Wellcome Trust Investigator Award, 2016
Editor of J. Mol. Biol 2016-present
Normanby Lecture in Microbiology (Trinity College Dublin) 2016
Hamied Foundation UK-India AMR Visiting Professorships; Academy of Medical Sciences, 2019
Emertius Professor, 2025

Fellow 2010-2016

Research Interests
The molecular basis of latency and dissemination during cryptococcosis

Other Information
Appointed Professor of Infectious Diseases, 2014
Awarded Royal Society Research Merit Award, 2015
Extended Fellowship to 30 September 2016
Elected to membership of the Institute 2016
Director, Institute of Microbiology & Infection, 2017-2020
Chief Scientific Adviser, Food Standards Agency, 2020-2025
Appointed Fellow of the American Academy of Microbiology, 2020
Appointed Gresham Professor of Physic, 2022
Appointed Fellow of the Academy of Medical Sciences, 2023
Appointed Fellow of the Royal Society of Biology, 2024
Chief Scientific Officer, UK Health Security Agency, 2025-present

Fellow 1988-1990

Research Interests
Signalling pathways in cancer and normal cells; insulin signalling and its defects in type II diabetes; mechanisms of insulin action and of glucose uptake and resistance; insulin secretion and its control. Mitochondrial metabolism, its regulation, control and functions of intracellular and intramitochondrial calcium.

Drug discovery.

Other Information
Resigned fellowship 30.9.90 on appointment as Head of Biochemical Pharmacology, Syntex Research Centre, Heriot-Watt University, Edinburgh
Awarded DSc, University of Bristol, 1992
Visiting Professor, University of Sunderland, 1994
Appointed Head of Diabetes Biology Department, Novo Nordisk, A/S, Denmark, from 1.11.95
Made Director of Diabetes Discovery, 1996
Elected a Member of the Institute, 1996
Director of Target Cell Biology, Novo Nordisk, 1998
Vice President, Target Cell Biology, Novo Nordisk, 2000
Appointed Vice President for Discovery Research UK, OSI Pharmaceuticals from 1.6.02
Vice President for Research, Prosidion from 1.12.04
Chief Scientific Officer (from 1.12.04) and Senior Vice President for Research (from 1.7.07) at (OSI) Prodidion until 31.12.08
Co-founded McC+R&D Consulting Ltd with Dr C Reynet, December 2009

Fellow 1984-1990

Research Interests
Molecular basis of viral pathogenicity using reoviruses (and mutagenesis studies). Molecular characterisation of rota viruses and their pathogenicity. Molecular epidemiological studies.

Other Information
Promoted to Senior Lecturer from 1.10.85
Appointed Reader in the Department of Biological Sciences from 1.10.87
Fellowship extended for 1 year to 30.9.90
Awarded Professor (Personal Chair) in Virology in the Department of Biological Sciences from 1.10.91
Chairman, Warwick University Graduate School, since 1995
Elected a Member of the Institute, 1996

Fellow 1994-1999

Research Interests
Role of glycoproteins in viral immunogenicity and pathogenicity with a focus on HIV and hepatitis.

Other Information
Presented with the 1995 Fleming Award by the Society of General Microbiology
Appointed Reader from 1.10.96
Resigned fellowship 31.7.99 on appointment as Head of Virology for Pfizer. Resigned from Pfizer, March 2000
Appointed Reader in Virology, University of Birmingham from October, 2000
Appointed Visiting Professor, Rockefeller University, New York, January 2001
Elected a Member of the Institute, 2003
Appointed to Chair of Molecular Virology, Institute of Biomedical Research, University of Birmingham, 2005
Hans Fischer Senior Fellowship at the Technical University of Munich, 2015-2018
Wellcome Trust Investigator Award, 2016-2021
Moved to Nuffield Department of Medicine, 2017

Fellow 1998-2003

Research Interests
Interest in inherited human disorders associated with unstable DNA, e.g. myotonic dystrophy and Huntington’s Disease. Studying molecular mechanisms that give rise to somatic and germ line genetic instability. The relation of these factors to downstream pathology.

Other Information
Presented the Genetical Society’s Balfour Lecture 1999
Promoted to Reader from 1.8.00
Awarded Personal Chair in Human Genetics, 2005
Elected a Member of the Institute, 2005
Awarded a Leverhulme Research Fellowship, 2007
Presented the Tenovus (Scotland) Medal Lecture, 2008
Awarded Muscular Dystrophy Campaign Science Communication Award, 2012
Awarded Muscular Dystrophy UK President’s Award for Scientist of the Year, 2017
Awarded Huntington’s Disease Society of America Researcher of the Year, 2019
Steinert Basic Science Award of the International Myotonic Dystrophy Consortium 2024
Muscular Dystrophy Association Sammy Davis Jr. Neuromuscular Disease Named Research Fellow 1994-1996

Fellow 1997-2002

Research Interests
Regulation of cell migration by ephrin mediated contact repulsion. Understanding how bi-directional signalling through Eph receptors and their ephrin ligands control the actin cytoskeleton and cell adhesion.

Other Information
Appointed Group Leader, MRC (LMCB) for 5 years and proleptic lecturer in the Anatomy and Developmental Biology Department, UCL, from 1.10.99
Resigned fellowship from 1.10.01 following award of an MRC Senior Research Fellowship
Elected a Member of the Institute, 2002
Moved to the University of Bristol, 2003
Promoted to Professor of Cell Biology, 2012
Appointed to Lister Institute Scientific Advisory Committee, 2017
Head of the School of Biochemistry, University of Bristol, 2014 – 2021

Fellow 2001-2005

Research Interests
Regulation of calcium signalling and calcium-dependent exocytosis in mast cells.

Other Information
Awarded the Wellcome Prize in Physiology 2002 by the UK Physiological Society
Elected to the Monsanto Senior Research Fellowship, Exeter College, Oxford from October 2002
Elected to Academia Europaea 2002
Proleptic lectureship in cardio-vascular physiology, 2002
Promoted to a Professorship in Physiology, 2002
Elected a Member of the Institute, 2006
Elected a Fellow of Academy of Medical Sciences, 2012
GL Brown Prize by the UK Physiological Society, 2012
Elected a Fellow of the Royal Society, 2019

Fellow 1983-1986

Research Interests
Structure-function relationships in antibodies and complement proteins.

Other Information
Resigned fellowship on appointment as Wellcome Trust Lecturer, Royal Free Hospital School of Medicine, 1986
Appointed Wellcome Trust Senior Lecturer, 1989
Appointed Reader in Structural Biochemistry, 14.2.94
Elected a Member of the Institute, 1996
Appointed Professor of Structural Biochemistry in the Royal Free & University College Medical School, 15.7.98

Fellow 1996-2002

Research Interests
The cell biology of glycosphingolipids and the role of these molecules in the pathophysiology of sphingolipid storage diseases, with emphasis on translating these findings into human therapy.

Other Information
Granted 6 months maternity leave from 1.4.97 to 30.9.97
Appointed to Research Reader 1.10.99
Awarded Merton Fellowship from 1.10.99
Elected a Member of the Institute, 2003
Professor of Biochemistry & Pharmacology, 2008
Editorial Board Member, Journal of Biological Chemistry, 2009-2014
Elected Fellow of Academy of Medical Sciences, 2011
Trustee Gordon Research Conferences, 2012
Elected Fellow of Royal Society of Biology, 2012
Royal Society Wolfson Research Merit Award, 2013
Elected Chair on Board of Trustees of Gordon Research Conferences, 2016
Elected to Academia Europaea, 2018
Head of Department of Pharmacology University of Oxford 2020
Elected Fellow of the Royal Society 2021
Awarded Thudichum medal, 2023

Fellow 1987-1995

Research Interests
Chemistry of signal transduction and calcium signalling pathways involving IP₃, cADPR and NAADP. Using a variety of synthetic, medicinal and biological chemistry methods to investigate enzyme inhibition, drug design and endocrinology, primarily in oncology.

Other Information
Appointed Lister Institute Research Professor of Pharmaceutical and Medicinal Chemistry at the University of Bath from 1.10.90, the Chair to continue in the Institute’s name until 30.9.95
Head of Medicinal Chemistry from 1990
Member of BBSRC Committee on Intracellular Signalling Programme, 1992-1996
Awarded DSc, University of Oxford, 1.2.93
Member of EPSRC Synthetic & Biological Chemistry College, 1995-1997
Professor of Medicinal & Biological Chemistry, 1995
Elected a Member of the Institute, 1996
Member of the RAE panel for Pharmacy, 200l
Non-Executive Director, Sterix Limited (2004-2009)
Member of the RAE2008 HEFCE Pharmacy Panel
Appointed visiting Professor of Medicinal Chemistry, University of Oxford (2006-2014)
Appointed to Wellcome Trust “Molecules Genes and Cells” Funding Panel (2006-2011)
Royal Society of Chemistry George & Christine Sosnovsky Prize in Cancer Therapy (2007/8)
RSC George & Christine Sosnovsky Endowed Lecturer 2007/8
Royal Society of Chemistry 2007 UCB-Celltech Industrially Sponsored Award & Medal in Chemical Biology
Fellow of the Academy of Medical Sciences, 2008
Elected Fellow of the Institute of Directors, 2008
Elected Fellow of the Institute of Biology, Chartered Biologist, 2008
Member of Sectional Committee 1, Academy of Medical Sciences, 2008-2011
Fellow, Royal Society of Arts, 2009
Appointed to the HEFCE Research Excellence Framework (REF) Expert Panel, 2009
Associate Editor, Journal of Steroid Biochemistry & Molecular Biology, 2009
Incorporated into “H-index ranking of living chemists” listing, 2009
Elected to Academia Europaea, 2009
GlaxoSmithKline International Achievement Award, 2009
Editor Biochemical Journal BJChemBio 2009-2016
Awarded Royal Society of Chemistry Biological & Medicinal Chemistry Section Malcolm Campbell Memorial Prize & Medal
Awarded Royal Society of Chemistry Interdisciplinary Prize & Medal, 2010 with an Endowed Lectureship for 2010
RSC Interdisciplinary Prize Endowed Lecturer, 2010-2011
Chairman, Medical Biopharma International Grant Review Panel, Danish Council for Independent Research, 2011
Member, International Advisory Board, Institute of Organic Chemistry & Biochemistry, Academy of Sciences of the Czech Republic, Prague, 2011-present
European Life Sciences Awards “Investigator of the Year”, 2012
Wellcome Trust Peer Review College, 2012-2015
Wellcome Trust Senior Investigator, 2013
Appointed to International Advisory Board ChemMedChem 2014-2017
IUPAC Advisory Board Member, Successful Drug Discovery, Vols 1-3, 2014-2018
Royal Society of Chemistry, Biological & Medicinal Chemistry Section, Endowed Lectureship in Medicinal Chemistry 2015/2016
Appointed Professor of Medicinal & Biological Chemistry, Department of Pharmacology, University of Oxford, 2015
Appointed Visiting Professor of Medicinal & Biological Chemistry, University of Bath, 2015-2018 (Now extended to 2024)
Elected Special Supernumerary Fellow of University College, Oxford, 2016
Appointed to Lister Institute Scientific Advisory Committee, 2017
Awarded Tu Youyou Award for Medicinal Chemistry & Chemical Biology related to Natural Product Chemistry, 2018
Member of the College of Experts, European Science Foundation, 2018-2021
Awarded D.Sc degree honoris causa by the University of Bath, 2020
Elected to Honorary Fellowship of the British Pharmacological Society (Hon FBPhS) 2022
Emeritus Professor of Medicinal & Biological Chemistry, University of Oxford 2022

Fellow 1997-2002

Research Interests
Signal transduction by receptor tyrosine kinases – particularly via endothelial growth factor (EGF) and vascular endothelial growth factor (VEGF).

Other Information
Elected a Member of the Institute, 2005

Fellow 1987-1993

Research Interests
Peroxiredoxins and redox oscillations in the circadian (24 hour) clockwork

Other Information
Moved to Francis Crick Institute, London, 2015
Elected to membership of the Institute, 2017
Moved to University of Pennsylvania, USA, 2019

Fellow 1987-1993

Research Interests
Epigenetic gene regulation during mammalian development and its deregulation in disease. Particular focus on imprinted genes and their function, mechanisms for gene imprinting, how faults in the mechanisms contribute to disease, and epigenetic reprogramming in early embryos.

Other Information
Promoted to Principal Scientific Officer 1.10.89
Fellowship extended by 1 year to 30.9.93
Head of the Laboratory of Developmental Genetics and Imprinting from 1992
Awarded the 1994 Wellcome Prize in Physiology
Elected a Member of the Institute, 1996
Elected to the MRC Scientific Advisory Board, 1997
Head, Programme of Developmental Genetics from 1997
Elected a Member of EMBO, 2003
Elected a Fellow of the Academy of Medical Sciences, 2003
Promoted to Associate Director, Babraham Institute, 2004
Head of Epigenetics & Chromatin Programme,
2008.Appointed Professor of Epigenetics in the Department of Physiology, Development & Neuroscience, University of Cambridge, 2008
Appointed to the Board of Management, Centre for Tophoblast Research, University of Cambridge, 2008
Elected as a Fellow of the Royal Society, 2010
Elected Member of Academia Europaea, 2011
Appointed Associate Faculty, Wellcome Trust Sanger Institute, Cambridge, 2011
Wellcome Trust Senior Investigator, 2011
Founding member of the Sanger Institute/EBI single cell genomics centre, 2013
BBSRC Great British Bioscience Pioneer 2014
Thomson Reuters Highly Cited Researcher, 2014
2018 Wellcome Investigator
Thomson Reuters highly cited researcher, 2018, 2019
Neuberger Memorial Lecture Hebrew University, 2018
Sammy Lee Memorial Lecture Crick Institute, 2018
Riccardo Cortese Lecture, 2018
ERC advanced grant, 2020
Acting director Babraham Institute, 2020
Appointed permanent Director Babraham Institute 2021
Appointed founding Director Altos Labs Cambridge Institute of Science 2022

Fellow 1988-1993

Research Interests
Investigation of the structure and functional relationships of biological macromolecules using X-ray crystallography. Specific areas of interest are rational drug design, analysis of the molecular basis of stability in proteins and the studies on protein – protein interactions in macromolecular complexes.

Other Information
Reader in the Department of Biochemistry, 1.10.90
Appointed Professor (Personal Chair) in the Department of Molecular Biology and Biotechnology and Director of The Krebs Institute for Biomolecular Research at Sheffield from 1.10.93
Elected a Member of the Institute, November 1993
Appointed Head of Department, 1997-2006
Elected a Member of the Institute’s Scientific Advisory Committee, 2005-2011

Fellow 1989-1996

Research Interests
The role of proteasomes in intracellular protein degradation in eukaryotic cells and various aspects of proteasome structure and function in animal cells.

Other Information
Lister Institute-Jenner Fellow
Fellowship extended by 2 years to 30.9.96
Promoted to Research & Analogous Grade III and made Hon Reader from 1.10.94
Transferred fellowship to Bristol on 28.3.96
Appointed Reader Department of Biochemistry, 1996
Wellcome Trust University Award from 1996 to 2001
Elected a Member of the Institute, 1997
Awarded a Personal Chair, 1.8.03

Fellow 1993-1999

Research Interests
The role of bacterial cell surface structures (polysaccharides primarily) in infectious diseases.  Specifically the synthesis of capsular polysaccharides in gram negative bacteria and the regulation of the capsule genes.

Other Information
Presented with the 1994 Fleming Award by the Society for General Microbiology
Awarded the W.H. Pierce Prize by the Society for Applied Bacteriology, 1994
Appointed Lister Institute Professor in Microbiology at the University of Manchester from 1.4.95
Elected a Member of the Institute, 2000
Elected to the Council of the Society for General Microbiology for period 2000-2004
Member of the Scientific advisory panel of the Meningitis Research Foundation, 2000-2006
Appointed Research Dean for the School of Biological Sciences, University of Manchester, from 1.1.02
Member of the BBSRC Studentships and Fellowships Panel, 2003-2008
MRC College of Experts, 2004-2008
Member of RCUK Academic Fellowship Panel, 2004-2008
Member of the Biological Sciences Panel SFI, 2008-2013
Chair of BBSRC Training and Awards Committee (TAC), 2009-2013
Member of the BBSRC Biosciences Skills and Careers Panel, 2009-2013
Member of the BBSRC Strategic LoLa Committee, 2009-2014
Member of the Immunology Panel Academy of Finland, 2012
Associate Dean for Research Faculty of Life Science, 2012-2016
Treasurer Microbiology Society UK, 2017-2022

Fellow 2002-2007

Research Interests
The regulation of cell fitness during embryonic development and its deregulation in disease.

Other Information
Elected a member of the Institute, 2009

Fellow 2001-2005

Research Interests
Mechanisms underlying embryonic neural precursor cell differentiation and therapeutic role in neural degeneration.

Other Information
Awarded a personal Chair in Clinical Neuroscience from 1.1.03 at the University of Wales, College of Medicine and an Honorary Chair at Cardiff University. (UWCM and UC have subsequently merged.)
Elected a Member of the Institute, 2006
Elected as Chair of the European Huntington’s Disease Network in 2018

Research Interests
Resolving mechanisms of gene regulation within the immune system using forward genetics

Fellow 1999-2004

Research Interests
The development of T-cell inducing vaccines against vivax malaria.

Other Information

Fellow 2013-2018

Research Interests
Decoding gene regulatory circuits controlling multipotency of neural crest

Other Information
Elected member of the Institute, 2018

Fellow 2014-2019

Research Interests
Mechanisms of aneuploidy in human oocytes

Other Information
EMBO Young Investigator Award, 2013
Biochemical Society Early Career Award, Cells, 2014
ERC starting grant (ChromOocyte), 2014
EMBL Alumni John Kendrew Young Scientist Award, 2015
Binder Innovation Award, 2016
Moved to Max Planck Institute, Germany, 2016
EMBO member, 2016
EMBO Gold Medal, 2018
Member of Leopoldina (German National Academy of Sciences), 2019
Gottfried Wilhelm Leibniz-Preis, German Research Foundation, 2019
Colworth Medal, Biochemical Society, 2019
Elected a member of the Institute, 2019
Honorary Professor at University of Göttingen, 2023

Fellow 1999-2004

Research Interests
Structural enzymology with specific attention to protein-based electron transfer reactions, hydrogen ion tunnelling, relationship between protein structures and function and applications of redox enzymes.

Other Information
Benefactors’ Research Scholarship, St John’s College, Cambridge, 1985-1988
Elected a Fellow of the Royal Society, 2020
Royal Commission for the Exhibition of 1851 Research Fellowship, 1988-1991
Henry Humphreys Research Prize, St John’s College, Cambridge, 1989
St John’s College Research Fellowship, Cambridge, 1989-1992
Royal Society University Research Fellowship, 1991-1999
Fellowship and Director of Studies, Churchill College, Cambridge, 1992-1995
Colworth Medal, Biochemical Society, 1999
Promoted to Professor of Biochemistry from 1.10.99
Lister Institute Research Professorship, 1999-2004
Appointed to Advisory Board of the MRC, October, 1999 and to the Biochemistry & Cell Biology Committee of BBSRC, May, 2000
Charmian Medal of the Royal Society of Chemistry, 2003
Awarded an ScD by the University of Cambridge, 2003
Moved to University of Manchester, 2005
Elected a Member of the Institute, 2005
Professor of Molecular Enzymology, 2005 – present
BBSRC Professional Research Fellow, 2006-2011
Assoc. Dean Research (FLS), University of Manchester, 2008 – present
Rita and John Carnforth Prize, RSC, 2009
Royal Society Wolfson Merit Award, 2009
Director, Manchester Interdisciplinary Biocentre, 2010
Director Manchester Institute of Biotechnology, 2010-2019
Director Synthetic Biology Research Centre, 2014
Director UK Future Biomanufacturing Research Hub, 2019
Elected Fellow Royal Society, 2020

Research Interests

Biomarkers of materno-fetal health: role of placental endocrine mediators in normal and obese pregnancies

Other Information

Awarded the Hans Sigrist Prize, 2020

Fellow 1997-2002

Research Interests
Transcriptional control of gene expression with a focus on transcription factors and co-activators/co-repressors, regulation by cellular signalling pathways including phosphorylation and sumoylation. Recent work focusses on the gene regulatory networks in cancer, chiefly in oesophageal adenocarcinoma.

Other Information
Appointed Reader from 1.8.98
Transferred fellowship to the University of Manchester from 1.1.99
Awarded the BACR (British Association for Cancer Research)/AstraZeneca “Young Scientist Award” 2000 and the Biochemical Society Colworth Medal, 2001
Awarded the Tenovus Medal 2002
Appointed Head of Division of Gene Regulation and Bioinformatics 1.4.02
Promoted to Professor of Molecular Biology 1.6.02
Elected a Member of the Institute, 2003
Wellcome Trust Senior Investigator Award, 2014
Promoted to Associate Dean for Research Technology, 2019

Fellow 1988-1992

Research Interests
Virology, particularly vaccinia virus, the smallpox vaccine, and how it enters and leaves cells and interferes with the innate immune system.

Other Information
Jenner Fellow of the Lister Institute, 1988
Reader in Bacteriology, Sir William Dunn School of Pathology, University of Oxford, 1989
Resigned Lister Institute Fellowship 30.6.1989, non-stipendiary Fellowship awarded 1.7.89 – 30.6.1992
Fleming Award from the Society for General Microbiology, 1992
Professor of Virology, University of Oxford, 1996
Fellow of the Royal Society of Biology, 2000
Fellow of the Academy of Medical Sciences, 2000
Wellcome Trust Principal Fellowship, 2000-2019
Professor of Virology, Faculty of Medicine, Imperial College London, 2000-11
Editor-in-Chief, Journal of General Virology, 2003-2008
Fellow of the Royal Society, 2003
Lister Institute Governing Body, 2003-2013
Chairman, WHO Advisory Committee on Variola Virus Research, 2004-present
MRC Infection and Immunity Board, 2004-2009
Wilhelm Feldberg Foundation Prize for Anglo-German Friendship in biological and medical science
Chairman, Virology Division, International Union of Microbiological Societies, 2005-2018
Teaching Excellence Award, Imperial College London, 2008
Founding Member of European Academy of Microbiologists (EAM), 2009
Corresponding Member of the Gesellschaft für Virologie (GfV), 2010
Professor of Pathology, Department of Pathology, University of Cambridge, 2011-present
Professorial Fellow, Emmanuel College, Cambridge, 2011-present
Member of the German National Academy of Sciences (Leopoldina), 2011
President, International Union of Microbiological Societies (IUMS), 2011-2014
Wellcome Trust Expert Review Group, Member 2011-2014
Chairman, Scientific Advisory Board, Friedrich-Loeffler Institute, German Federal Ministry of Food, Agriculture and Consumer Protection 2015-19
American Society for Microbiology – GlaxoSmithKline, International Member of the Year Award, 2012
Member, Biomedical Panel of the Research Grant Committee of Hong Kong, 2012-2018
Member, Research Grants Council, Hong Kong, 2015-
Member, Scientific Advisory Board Centre of Structural Systems Biology, Hamburg, Germany
Awarded Loeffler Prize Lecture by Friedrich-Loeffler Institute/Alfried Krupp Wissenschaftskolleg Greifswald, Germany, 2016
Marjory Stephenson Prize Lecture 2018, the Microbiology Society
Awarded Leeuwenhoek Medal and Prize Lecture Royal Society, 2019

Fellow 2007-2012

Research Interests
Control of infection and autoimmunity by an inhibitory Fc receptor FcγR11b

Other Information
Khoo Oon Teik Professor of Nephrology, National University of Singapore, 2007
Promoted to Professor of Medicine, 2009 and Head of Department of Medicine, Cambridge, 2010
Chairman, European Vasculitis Genetics Consortium and Director of FOCIS Int Center of Excellence, 2011
Elected a member of the Institute, 2013

Fellow 1990-1994

Research Interests
Structural studies of the serpin family of proteins.

Other Information
Granted 1 year’s leave of absence from 1.3.91 for crystallography training, Dept of Medical Microbiology and Infectious Diseases at the University of Alberta, Canada
Renewed fellowship 1.4.93; fellowship now to end 30.9.97
Resigned fellowship 1.12.94 to take up research in the Department of Medical Microbiology, University of Alberta, Edmonton, Canada
Granted, exceptionally, 6 months’ fellowship from 1.10.95 to 31.3.96 to complete research project at Cambridge
Professor’s Prize in Clinical Biochemistry, 1966
Awarded a Wellcome Senior Clinical Fellowship from 1.10.98 in the Department of Haematology, School of Clinical Medicine, Cambridge
Elected a Member of the Institute, 2000

Fellow 2009-2014

Research Interests
Investigating the role of the RIDDLE syndrome gene in promoting repair of DNA damage

Other Information
Awarded CR-UK Senior Fellowship, 2011-2017
Elected a member of the Institute 2015
Promoted to Professor of Cancer Genetics, 2015
Joseph Chamberlain Award for Scientific Advancement, 2017
CR-UK Programme Grant, 2017-2022

Fellow 1993-1998

Research Interests
Protein targeting and organelle biogenesis in yeasts.  Translocation across membranes.  Functional genomics and yeast proteome.  Molecular chaperones.

Other Information
Lister Institute-Jenner Fellow
Appointed Reader in the Department of Biochemistry and Molecular Biology, University of Manchester from 1.10.94
Society for General Microbiology Fleming Award, 1997
Awarded the 1998 Balfour Prize by the Genetical Society
Appointed to a Personal Chair in Genetics from 1.8.98
Elected a Member of the Institute, 1999
Representative of the University of Manchester 1.2.01
Education Dean, School of Biological Sciences, 2002
Associate Dean, Faculty of Life Sciences, 2004-2007
Vice President, University of Manchester, 2007-2011
Deputy Vice-Chancellor, Curtin University, Australia, 2011-2014
President and Vice Chancellor, Flinders University, Australia, 2015

Fellow 2014 – 2019

Research Interests
Mechanisms of microtubule organisation and intracellular transport

Other Information
Wellcome Trust Investigator Award, 2016
Elected a Member of the Institute, 2018
Promoted to Professor, 2020
Wellcome Investigator award, 2022

Fellow 1998-2003

Research Interests
Understanding how during animal development cells become polarized in developing tissues or organs in a co-ordinated fashion.  Using the cuticle of the fruit fly, Drosophila, as the model system and a variety of genetic and cell biological approaches.

Other Information
Lister Institute-Jenner Fellow
Promoted to Reader from 1.10.01
Awarded a Wellcome Trust Senior Fellowship from 2003
Elected a Member of the Institute, 2004
Promotion to Professor of Developmental Genetics, 2005
Awarded Wellcome Trust Senior Fellowship, 2008
Awarded Wellcome Trust Senior Fellowship, 2013
Wellcome Trust Senior Fellowship in 2018

Fellow 2005-2010

Research Interests
Mechanisms regulating chromosome duplication and segregation in the cell division cycle.

Other Information
Awarded Professorship December 2007
Awarded the Hook Medal from the British Society for Cell Biology, 2007
Elected an EMBO member, 2008
Fellow of the Royal Society of Edinburgh, 2009
Elected a Member of the Institute, 2011

Fellow 1992-1997

Research Interests
Intra-cellular calcium signalling: specifically the regulation of calcium entry pathways, the structure and function of intra-cellular calcium channels, signalling receptors and G-proteins.

Other Information
Appointed Reader, Department of Pharmacology 1995 Elected a Member of the Institute, 1998
Awarded ScD by the University of Cambridge, 1999
Appointed Professor of Cellular Pharmacology, 1.10.01
Biochemical Society, Council 2002-2005
Elected member of Academia Europaea, 2013
Wellcome Trust Senior Investigator 2014
Elected Fellow Academy of Medical Sciences, 2016
Retired September 2022

Fellow 2010-2015

Research Interests
Bioinformatics and network biology for unraveling regulation of T helper cell differentiation

Other Information
Elected as EMBO member 2012
Moved to EMBL-EBI & Wellcome Trust Sanger Inst, 2013
Fellowship extended to 31 December 2015
EMBO Gold Medal 2015
Elected Fellow Academy of Medical Sciences 2015
Head of Cellular Genetics, WSI 2016
Elected a Member of the Institute 2016
Elected a Fellow of the Royal Society, 2020
Head of Cellular Genetics, WSI 2016-2024
Co-founder and co-leader of Human Cell Atlas International consortium 2016-
FEBS | EMBO Women in Science Award 2023
Co-director of CIFAR Macmillan Research Program: The Multiscale Human 2023-
Co-founder, consultant and CSO of Ensocell Therapeutics 2023-
Feldberg Foundation Prize 2024
Raman Chair of the Indian Academy of Science 2024
VP Translational Research, Respiratory & Immunology, GSK 2024-
Moved to: Cambridge Stem Cell Institute, University of Cambridge 2024-
Professor of Stem Cell Medicine, Cambridge Stem Cell Institute and Department of Medicine, University of Cambridge 2024-
Elected into the American Academy of Arts and Sciences 2025

Fellow 2006-2012

Research Interests
Identifying and characterizing genes that control cell fate choice and social behavior.

Other Information
Fellowship extended until 31.08.12
Elected a member of the Institute, 2013
Awarded Wolfson Research Merit Award, 2013
Moved to University College London, 2017

Fellow 2001-2003

Research Interests
Molecular mechanisms of mitochondria biogenesis with particular emphasis on the targeting, membrane translocation and assembly processes for membrane proteins using yeast. Role of Tim proteins as chaperones.

Oxidative folding and redox signalling in mitochondria in health and disease. Peptide-based pharmaceutical targeting of mitochondria for theranostic applications

Other Information
Resigned fellowship, 30 September 2003
Appointed Associate Professor, University of Crete in the Institute of Biology & Molecular Biology, 1.10.03
Consumables expenditure extended until 1.10.04
Elected a Member of the Institute, 2005
Elected EMBO member 2013
Royal Society Wolfson Research Merit Award, 2013
Moved to University of Glasgow, 2013
Cathcart Chair, University of Glasgow, 2013
Fellow of the Royal Society of Edinburgh, 2016
Elected Fellow of the Royal Society of Biology, 2020
Elected Fellow of the Royal Society of Chemistry, 2021
Director of Research, School of Molecular Biosciences, University of Glasgow, 2022
Elected member of Academia Europaea (MAE), 2022

Fellow 2001-2006

Research Interests
MAPK signalling in cancer.

Other Information
Fellowship extended to 16.2.07
Elected a Member of the Institute, 2007
Promoted to Senior lecturer 2012

Fellow 2007-2011

Research Interests
Dissecting the links between O-GlcNAc and intellectual disability

Other Information
Awarded professorship June 2006
Elected Fellow of the Royal Society of Edinburgh, 2010
Elected a Member of the Institute, 2012
Awarded Novo Nordisk Foundation “Laureate” grant, 2022

Fellow 1996-2002

Research Interests
Understanding the role of non-covalent interactions in recognition processes involving proteins. Specifically looking at the role of conformational dynamics and conformational transitions in the recognition of phosphoinositols, the assembly of cystatins, in prion proteins and in ligand binding and ligand recognition of mobile protein domains.

Other Information
Appointed to a personal chair from 1.10.99 as Professor of Molecular Biology
Granted 7 months unpaid leave for training at the Technical Research Centre of Finland, Helsinki from 15.3.01 and fellowship extended until 30.4.02
Elected a Member of the Institute, 2003
Appointed member of the Institute’s SAC, 2012 – 2017

Fellow 2007-2013

Research Interests
Transcriptional control of mesodermal cell differentiation in vertebrates

Other Information
Transferred fellowship to King’s College London, 2010
Fellowship extended to 30.09.13 due to move to KCL
Elected a member of the Institute 2014

Fellow 1999-2005

Research Interests
Structural biochemistry of membrane proteins, immune response proteins and metabolic enzymes for diet and health; exploring structure-function relationships at the molecular level

Other Information
Transferred fellowship to University of Reading 1.10.01
Reader in Structural Biology from 1.10.01
Granted unpaid leave of absence from 1.10.01 to 31.3.02
Fellow of the Royal Society of Medicine, 2001
Fellow and Chartered Biologist of the Royal Society of Biology, 2002
Granted maternity leave from 1.8.03 for 4 months
Elected a Member of the Institute, 2006
Fellow of the Royal Society of Chemistry, 2013
Fellow of the Higher Education Academy, 2018
Promoted to Professor of Structural Biochemistry from 1.08.2018

Fellow 2015-2021

Research Interests
The nature, mechanism and function of RNA polymerase II modifications in health and disease

Other Information
EMBO Young Investigator Award, 2014
Wellcome Trust Investigator Award, 2015
Moved to University of Exeter, 2017
Extended Fellowship to September 2021.
Elected to membership of the Institute, 2020

Fellow 1996-2001

Research Interests
Regulation of RNA polymerase III transcription, its mode of action and control and its role in cell growth and cancer.

Other Information
Lister Institute-Jenner Fellow
Awarded the ‘Young Scientist of the Year’ award for 1999 by the British Association for Cancer Research in association with Zeneca
Promoted to Reader from 1.10.99
Appointed Professor of Gene Transcription from 1.10.99
Elected a Member of the Institute, 2002
Selected as The Young Cancer Researcher of 2003 by the European Association for Cancer Research
Elected a Fellow of the Royal Society of Edinburgh, 2004
Awarded the Tenovus Medal for 2004
Elected a Fellow of the Academy of Medical Science, 2005
Elected a member of EMBO, 2009
Moved to University of York, 2013

Fellow 2001-2006

Research Interests
Role of scaffold proteins in regulating the specificity of the JNK signalling pathway: a critical mediator of stress responses in cells.

Other Information
Lister Institute-Jenner Fellow
Elected a Member of the Institute, 2007
Promoted to Senior Lecturer, 2010

Fellow 1984-1994

Research Interests
Brain diseases and ageing with a particular focus on the molecular features of Alzheimer’s Disease.

Other Information
Granted extension of fellowship by 3 years to 30.9.92 to continue research and, exceptionally, to undertake clinical training for Membership of the Royal College of Psychiatry. Granted further extension of 1 year to 30.9.93

Awarded MRCPsych, Spring 1993

Granted further extension of 6 months to 31.3.94

Appointed Clinical Lecturer/Senior Registrar in Old Age Psychiatry, Cambridge, for 4 years from 1.3.94

Appointed Professor of Psychiatric Geratology, University of Aberdeen from 1.10.97

Elected a Member of the Institute, 2001

Fellow 1997-2002

Research Interests
Establishment of spatial patterns and polarity in the early embryo. Determination of cell fate in developing mammalian embryos.

Other Information
Granted maternity leave from 1.12.01 to 28.2.02
Resigned fellowship 31.3.02 following the award of a Wellcome Trust Senior Research Fellowship from 1.4.02
Elected a Member of the Institute, 2003
Awarded Professorship, University of Cambridge, 2010
Appointed member of the Institute’s Scientific Advisory Committee, 2019