Dr Kirby Swatek
Title of Research Project Irreversible inactivation of ubiquitin and ubiquitin-like proteins
Nurturing the future leaders in biomedical research
Nurturing the future leaders in biomedical research
Dr Amanda Chaplin
Title of Research Project Cryo-EM studies of human DNA repair complexes: DNA-PK and interacting partners
Professor Stephen J Perkins
Fellow 1983-1986 Area of Current Research Interests Structure-function relationships in antibodies and complement proteins. Other Information Resigned fellowship on appointment as Wellcome Trust Lecturer, Royal Free Hospital School of Medicine, 1986. Appointed Wellcome Trust Senior Lecturer, 1989. Appointed Reader in…
Professor Nigel S Scrutton
Fellow 1999-2004 Area of Current Research Interests Structural enzymology with specific attention to protein-based electron transfer reactions, hydrogen ion tunnelling, relationship between protein structures and function and applications of redox enzymes. Other Information Benefactors’ Research Scholarship, St John’s College, Cambridge,…
Professor Kostas Tokatlidis
Fellow 2001-2003 Area of Current Research Interests Molecular mechanisms of mitochondria biogenesis with particular emphasis on the targeting, membrane translocation and assembly processes for membrane proteins using yeast. Role of Tim proteins as chaperones. Oxidative folding and redox signalling in…
Professor Peter J Cullen
Fellow 1999-2003 Area of Current Research Interests We study the molecular mechanisms of protein sorting in mammalian cells and the fundamental role it plays in cell, tissue and organism-level function. Specifically, our mechanistic dissection of protein sorting within the endosomal…
Professor Jeremy P Derrick
Fellow 1996-2001 Area of Current Research Interests Structure and function of bacterial cell surface proteins. Engineering of virus-like particles for use as scaffolds for antigen assemblies in vaccine design. Immunological responses to vaccines and biotherapeutic drugs. Other Information Promoted to…
Professor Anthony Maxwell
Fellow 1991-1997 Area of Current Research Interests DNA gyrase and other DNA topoisomerases: structure, function and mechanisms of action; role in DNA replication, recombination and the control of gene expression. Antibiotic action and discovery. Galleria mellonella as a model for…
Professor Bernard A Connolly
Fellow 1989-1994 Area of Current Research Interests Protein DNA interactions, DNA polymerases, DNA repair, restriction and modification. Other Information Promoted to Senior Lecturer from 1.1.91. Appointed Lister Institute Professor of Biochemistry at the University of Newcastle-upon-Tyne from 1.1.92, the Chair…
Professor Mark J Buttner
Fellow 1994-1998 Area of Current Research Interests The cellular and developmental biology of the filamentous, antibiotic-producing bacteria Streptomyces. Fundamental aspects of bacterial transcription. The regulatory networks and cyclic nucleotide signalling events that control sporulation in Streptomyces. Other Information Appointed Group…