Dr Johnathan Cooper-Knock

Title of Research Project Detailed cell-specific genetics of amyotrophic lateral sclerosis (ALS). Website

Title of Research Project Detailed cell-specific genetics of amyotrophic lateral sclerosis (ALS). Website

Fellow 1988-1993 Research Interests Investigation of the structure and functional relationships of biological macromolecules using X-ray crystallography. Specific areas of interest are rational drug design, analysis of the molecular basis of stability in proteins and the studies on protein –…

Fellow 1998-2003 Research Interests Understanding how during animal development cells become polarized in developing tissues or organs in a co-ordinated fashion. Using the cuticle of the fruit fly, Drosophila, as the model system and a variety of genetic and cell…

Fellow 1996-2002 Research Interests Understanding the role of non-covalent interactions in recognition processes involving proteins. Specifically looking at the role of conformational dynamics and conformational transitions in the recognition of phosphoinositols, the assembly of cystatins, in prion proteins and in…

Fellow 1997-2002 Research Interests Control of chromatin activity during vertebrate development. Particular focus is on the role of histone modifying enzymes in transcriptional programming of cell fate decisions in the central nervous system. Control of chromatin activity during vertebrate development.…

Research Interests The repair of oxidative and topoisomerase induced chromosomal strand breaks and human disease Other Information: Moved to University of Sheffield, 2014 Awarded Professorship, 2015 Elected as Fellow of the Royal Society of Chemistry, 2016 Extended Fellowship until September…