Professor Sarah Dimeloe

Title of Research Project Co-operative metabolic synthesis as a fourth signal for T cell priming Website
Title of Research Project Co-operative metabolic synthesis as a fourth signal for T cell priming Website
Fellow 1996-2002 Research Interests The cell biology of glycosphingolipids and the role of these molecules in the pathophysiology of sphingolipid storage diseases, with emphasis on translating these findings into human therapy. Other Information Granted 6 months maternity leave from 1.4.97…
Fellow 2002-2007 Research Interests The regulation of cell fitness during embryonic development and its deregulation in disease. Other Information Elected a member of the Institute, 2009
Fellow 2001-2003 Research Interests Molecular mechanisms of mitochondria biogenesis with particular emphasis on the targeting, membrane translocation and assembly processes for membrane proteins using yeast. Role of Tim proteins as chaperones. Oxidative folding and redox signalling in mitochondria in health…
Fellow 1999-2005 Research Interests Structural biochemistry of membrane proteins, immune response proteins and metabolic enzymes for diet and health; exploring structure-function relationships at the molecular level Other Information Transferred fellowship to University of Reading 1.10.01 Reader in Structural Biology from…
Fellow 1984-1989 Research Interests Signal transduction with emphasis on the control of metabolism. Specific interests are insulin action, the biochemistry of obesity and Type 2 diabetes. Other Information Promoted to Senior Lecturer from 1.8.87 Appointed Professor of Molecular Enzymology in…
Fellow 1983-1988 Research Interests Characterising the steroids present in nervous tissue, studying their levels and source (peripheral endocrine glands and endogenously produced) and the mechanisms which regulate their production. Other Information Appointed Senior Lecturer, 1992 Elected a Member of the…
Fellow 1992-1998 Research Interests Regulation of glucose transport in insulin-sensitive tissues in health and disease. Single molecule imaging of plasma membrane proteins. Cellular and Subcellular analysis of metabolic processes. Other Information Appointed Senior Lecturer retrospectively from l.7.92 Promoted to Reader…
Fellow 1983-1998 Research Interests Understanding the molecular mechanisms of cell injury and death in human disease and in response to toxins. The role of antioxidants in nutrition, health and disease. Natural and synthetic antioxidants as therapeutic agents, especially for neurodegenerative…
Fellow 1995-2000 Research Interests Mechanisms of oxygen sensing and impact of hypoxia. The role of ion channels, neurotransmitters and neuromodulators in the maturation of oxygen sensing and the effect of hypoxia upon cardiorespiratory disease. Other Information Promoted to Senior Lecturer,…