Fellow 1999-2003

Research Interests
We study the molecular mechanisms of protein sorting in mammalian cells and the fundamental role it plays in cell, tissue and organism-level function. Specifically, our mechanistic dissection of protein sorting within the endosomal network has provided the framework to understand and interpret the de-regulation of endosomal protein sorting observed in a broad array of human diseases. These include cardiovascular disease and neurological disorders, most notably Alzheimer disease and Parkinson disease, as well as metabolic disorders such a type 2 diabetes.

Other Information
Promoted to Professor, 2002
Elected a Member of the Institute, 2005
Royal Society Merit Award Holder, 2008
Biochemical Society Morton Lecture, 2010
Keith Stanley Lecture, 2011
Elected Fellow of the Academy of Medical Sciences, 2020
Royal Society Noreen Murray Research Professorship, 2021
Elected Member of EMBO, 2021